Table 1.
PBSC graft cell subset frequencies and cell doses from 78 healthy donors
| Frequencies of graft cell subsets, (%) |
Doses of graft cell subsets infused, 106 cells/kg of body weight |
|||
|---|---|---|---|---|
| Mean ± SD | Median (min-max) | Mean ± SD | Median (min-max) | |
| CD34+ | 2.1 ± 1.7 | 1.6 (0.4-12.6) | 5.9 ± 2.8 | 5.7 (1.1-16.8) |
| NK cells | 3.6 ± 2.5 | 3.2 (0.5-18.4) | 13.2 ± 12.3 | 10.5 (0.46-80.8) |
| B cells | 11.9 ± 6.5 | 10.5 (0.9-34.8) | 46.1 ± 52.1 | 33.9 (5.1-162.3) |
| T cells | 45.6 ± 11.4 | 45.30 (21.8-75.4) | 170.5 ± 119 | 145 (16.8-684.1) |
| CD4+ T cells | 30.4 ± 8.6 | 29.8 (12.6-56.5) | 115 ± 86.9 | 89.9 (8.8-511) |
| CD8+ T cells | 13.1 ± 5.8 | 11.8 (4.1-29.2) | 47.7 ± 34.6 | 36.8 (5.4-154) |
| Tregs | 3.8 ± 1.6 | 3.5 (0.9-8.2) | 6.68 ± 6.5 | 4.8 (0.4-41.3) |
| CD3+CD161+ | 12.7 ± 6.9 | 12.6 (1.6-32.6) | 10.1 ± 11.3 | 6.4 (0.6-62.1) |
| iNKT cells | 0.139 ± 0.23 | 0.043 (0.001-1.07) | 0.2 ± 0.312 | 0.052 (0.002-1.4) |
| iNKT CD4− | 0.091 ± 0.175 | 0.019 (0.001-0.76) | 0.113 ± 0.2 | 0.031 (0.001-1.04) |
| iNKT CD4+ | 0.061 ± 0.12 | 0.015 (0.001-0.68) | 0.091 ± 0.175 | 0.025 (0.001-1.09) |
CD34+, NK, B, T, CD4+, and CD8+ T-cell frequencies are shown as percentage of the total live cells. Tregs, CD3+CD161+, and iNKT-cell frequencies are shown as percentage of the T cells.