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. 2018 Sep 14;29(9):827–838. doi: 10.1097/CAD.0000000000000673

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Copyright © 2018 The Author(s). Published by Wolters Kluwer Health, Inc.

This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0/

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Fig. 1 — CRC cell lines exposed to ENMD-2076 to establish their IC₅₀s. Cell lines were treated with increasing concentrations of ENMD-2076 and IC₅₀ values were calculated. A broad range of sensitivity to the agent was observed. HCT116, GEO, LS1034, and LS123 (black arrows) were selected for further analysis.