Table 1. Comparison of demographic, clinical, and biochemical data, and liver stiffness and CAP of subjects from the risk group and control group.
Variable | Risk group n = 215 |
Control group n = 80 |
P value |
---|---|---|---|
Age (yr) | 58 ± 12 | 62 ± 13 | 0.03 |
Male gender | 35 (44%) | 91 842%) | 0.9 |
Tobacco consumption | 45 (20%) | 17 (19%) | 0.7 |
Diabetes Mellitus | 60 (28%) | - | <0.001 |
Dyslipidemia | 150 (70%) | - | <0.001 |
Obesity (BMI≥30 Kg/m2) | 113 (52%) | - | <0.001 |
Metabolic syndrome | 98 (46%) | - | <0.001 |
Number of risk factors | |||
1 | 86 (40%) | - | <0.001 |
2 | 66 (31%) | - | |
≥3 | 63 (29%) | - | |
BMI (Kg/m2) | 31 ± 5 | 25 ± 2 | <0.001 |
Waist circumference (cm) | 104 ± 13 | 91 ± 10 | <0.001 |
Glucose (mg/dL) | 112 ± 40 | 89 ± 10 | <0.001 |
Total cholesterol (mg/dL) | 204 ± 44 | 198 ± 26 | 0.15 |
HDL- cholesterol (mg/dL) | 49 ± 14 | 58 ± 16 | <0.001 |
LDL-cholesterol(mg/dL) | 129 ± 33 | 123± 24 | <0.001 |
Triglycerides (mg/dL) | 138 ± 83 | 83 ± 24 | <0.001 |
ALT (IU/L) | 26 ± 16 | 24 ± 11 | 0.16 |
GGT (IU/L) | 34 ± 35 | 27 ± 40 | 0.16 |
Serum creatinine (mg/dL) | 0.7 ± 0.1 | 0.7 ± 0.2 | 0.6 |
Albumin (g/L) | 44 ± 2 | 43 ± 2 | 0.8 |
Ferritin (ng/mL) | 125 ± 137 | 104 ± 91 | 0.21 |
Glycated hemoglobin (%) | 6.2 ± 1 | 5.5 ± 0.3 | <0.001 |
HOMA | 5.7 ± 8.6 | 2.2 ± 1.4 | <0.001 |
LS (kPa) | 4.9 ± 2.7 | 4.2 ± 0.9 | 0.002 |
CAP (dB/m) | 268 ± 64 | 243 ± 49 | 0.001 |
Values are number and percentages (in brackets) or mean±SD. BMI, body mass index; ALT, alanine aminotransferase; GGT, gamma glutamyltranspeptidase; HOMA, Homeostasis model assessment; LS, liver stiffness; CAP, controlled attenuation parameter