Table 5. Comparison of baseline characteristics of subjects with risk factors for NAFLD categorized according to the presence (S3) or absence (S0-1-2) of severe steatosis measured by CAP values.
| Variable | CAP < 280dB/m S0-1-2 |
CAP ≥ 280dB/m S3 |
|
|---|---|---|---|
| n = 122 | n = 93 | ||
| Age (yr) | 62 ± 13 | 63 ± 12 | 0.5 |
| Male gender | 48 (39%) | 43 (46%) | 0.3 |
| Tobacco consumption | 24 (19%) | 19 (21%) | 0.63 |
| Diabetes Mellitus | 25 (21%) | 35 (38%) | 0.009 |
| Dyslipidemia | 83 (68%) | 67 (72%) | 0.55 |
| Obesity (BMI≥30kg/m2) | 49 (41%) | 64 (69%) | <0.001 |
| Metabolic syndrome | 46 (38%) | 52 (56%) | 0.009 |
| Number of risk factors | |||
| 1 | 21 (18%) | 8 (9%) | 0.003 |
| 2 | 44 (37%) | 30 (33%) | |
| >3 | 46 (38%) | 52 (56%) | |
| BMI (Kg/m2) | 29 ± 5 | 33 ± 5 | <0.001 |
| Waist circumference (cm) | 100 ± 11 | 109 ± 11 | <0.001 |
| Glucose (mg/dL) | 103 ± 36 | 124 ± 43 | <0.001 |
| Total cholesterol (mg/dL) | 207 ± 45 | 199 ± 43 | 0.18 |
| HDL- cholesterol (mg/dL) | 52 ± 16 | 45 ± 11 | <0.001 |
| LDL-cholesterol(mg/dL) | 130 ± 34 | 126 ± 32 | 0.37 |
| Triglycerides (mg/dL) | 122 ± 69 | 159 ± 94 | 0.001 |
| ALT (IU/L) | 23 ± 12 | 30 ± 19 | 0.006 |
| GGT (IU/L) | 29 ± 28 | 41 ± 43 | 0.02 |
| Creatinine (mg/dL) | 0.7 ± 0.2 | 0.8 ± 0.2 | 0.6 |
| Albumin (g/L) | 44 ± 2 | 44 ± 2 | 0.9 |
| Ferritin (ng/mL) | 109 ± 114 | 146 ± 161 | 0.05 |
| Glycated hemoglobin (%) | 5.9 ± 0.9 | 6.4 ± 1.1 | 0.001 |
| HOMA | 3.7 ± 3.3 | 8.2 ± 12 | 0.001 |
| FLI | 56 ± 25 | 78 ± 20 | <0.001 |
| LS (kPa) | 4.4 ± 1.2 | 5.6 ± 3.8 | <0.001 |
| CAP (dB/m) | 224 ± 41 | 325 ± 36 | <0.001 |
Values are number and percentages (in brackets) or mean±SD. BMI, body mass index; ALT, alanine aminotransferase; GGT, gamma glutamyltranspeptidase; HOMA, Homeostasis model assessment; LS, liver stiffness; CAP, controlled attenuation parameter