Table 7. Comparison of characteristics of subjects with risk factors for NAFLD categorized according to liver stiffness.
| Variable | Normal LS N = 188 |
Increased LS* N = 27 |
P value |
|---|---|---|---|
| Age | 62 ± 12 | 65 ± 13 | 0.2 |
| Male gender | 76 (83%) | 15 (16%) | 0.15 |
| Diabetes Mellitus | 46 (24%) | 14 (52%) | 0.005 |
| Dyslipidemia | 135 (72%) | 15 (56%) | 0.12 |
| Obesity (BMI≥30kg/m2) | 94 (50%) | 19 (73%) | 0.03 |
| Metabolic syndrome | 83 (44%) | 15 (56%) | 0.3 |
| BMI (Kg/m2) | 30 ± 5 | 35 ± 6 | <0.001 |
| Waist circumference (cm) | 102 ± 11 | 115 ± 13 | <0.001 |
| Glucose (mg/dL) | 107 ± 34 | 146 ± 58 | 0.002 |
| Total cholesterol (mg/dL) | 206 ± 45 | 188 ± 36 | 0.05 |
| HDL- cholesterol (mg/dL) | 50 ± 15 | 46 ± 13 | 0.2 |
| LDL-cholesterol(mg/dL) | 130 ± 34 | 118 ± 28 | 0.1 |
| Triglycerides (mg/dL) | 134 ± 80 | 165 ± 97 | 0.065 |
| ALT (IU/L) | 25 ± 13 | 36 ± 24 | 0.02 |
| GGT (IU/L) | 31 ± 28 | 57 ± 69 | 0.06 |
| Albumin (g/L) | 44 ± 2 | 43 ± 3 | 0.6 |
| Ferritin (ng/mL) | 115 ± 109 | 194 ± 253 | 0.1 |
| Glycated hemoglobin (%) | 6 ± 0.9 | 6.8 ± 1.3 | 0.007 |
| HOMA | 4.7 ± 6.2 | 12.6 ± 16.61 | 0.03 |
| FLI | 63 ± 25 | 85 ± 18 | <0.001 |
| CAP (dB/m) | 261 ± 59 | 316 ± 71 | <0.001 |
*>7 Kpa with M probe or >6.2 kPa with XL probe.
Values are number and percentages (in brackets) or mean±SD. BMI, body mass index; ALT, alanine aminotransferase; GGT, gamma glutamyltranspeptidase; HOMA, Homeostasis model assessment; LS, liver stiffness; CAP, controlled attenuation parameter.