Table 1. Characteristics of coronary artery disease patient group of survivors, sudden cardiac death (SCD) and all-cause mortality (ACM).
| Survivors | SCD | ACM | |
|---|---|---|---|
| n = 1740 | n = 50 | n = 205 | |
| Age (years) | 66 (9) | 69 (7)* | 72 (8)‡ |
| Sex (male) | 1166 (67%) | 39 (78%) | 161 (79%)† |
| BMI (kg/m2) | 28.3 (4.5) | 28.7 (4.8) | 28.5 (5.1) |
| Systolic BP (mmHg) | 147 (24) | 146 (22) | 146 (27) |
| Diastolic BP (mmHg) | 81 (11) | 80 (11) | 79 (13) |
| Smokers | 146 (8%) | 7 (14%) | 21 (10%) |
| History of AMI (n) | 826 (48%) | 28 (56%) | 103 (50%) |
| History of PCI/CABG (n) | 1386 (80%) | 42 (84%) | 158 (77%) |
| Syntax score | 0 (0–5) | 3 (0–8) | 2 (0.9)‡ |
| CCS class (n) | ‡ | ‡ | |
| 1 | 1000 (59%) | 15 (31%) | 79 (39%) |
| 2 | 594 (35%) | 26 (54%) | 80 (39%) |
| 3 | 113 (7%) | 7 (15%) | 41 (20%) |
| Type of Glucose Metabolism Disorder | † | ‡ | |
| Impaired Glucose Tolerance (n) | 280 (16%) | 7 (14%) | 34 (17%) |
| Impaired Fasting Glucose (n) | 98 (6%) | 2 (4%) | 5 (2%) |
| Diabetes (n) | 709 (41%) | 34 (68%) | 124 (61%) |
| Duration of diabetes (months) | 60 (24–132) | 54 (21–213) | 96 (24–228)† |
| Medication (n) | |||
| β-blocker | 1518 (87%) | 45 (90%) | 186 (91%) |
| ACEi/ARB | 1182 (68%) | 37 (74%) | 148 (72%) |
| CCB | 422 (24%) | 11 (22%) | 52 (25%) |
| Diuretics | 554 (32%) | 26 (52%)† | 112 (55%)‡ |
| Lipids | 1598 (92%) | 44 (88%) | 179 (87%)* |
| Echogardiography | |||
| LVEF (%) | 64 (9) | 58 (14)‡ | 61 (13)‡ |
| LVMI (g/m2) | 107 (27) | 118 (30)† | 118 (31)‡ |
| Laboratory analyses | |||
| HbA1c (%) | 6.3 (0.9) | 6.9 (1.7)‡ | 6.8 (1.5)‡ |
| Total cholesterol (mmol/L) | 4.0 (0.9) | 4.4 (1.1)† | 4.0 (1.0) |
| HDL cholesterol (mmol/L) | 1.3 (0.3) | 1.2 (0.4) | 1.2 (0.3)* |
| LDL cholesterol (mmol/L) | 2.3 (0.8) | 2.6 (1.0)† | 2.3 (0.9) |
| Triglycerides (mmol/L) | 1.2 (0.9–1.7) | 1.4 (0.9–1.9) | 1.2 (0.9–1.7) |
| eGFR (mL/min) | 95 (34) | 87 (33) | 81 (35)‡ |
| U-Alb/Crea | 0.8 (0.6–1.3) | 1.1 (0.9–2.4)‡ | 1.3 (0.7–2.6)‡ |
| hs-CRP (mg/L) | 0.9 (0.5–1.9) | 1.8 (0.7–6.0)† | 1.4 (0.7–3.7)‡ |
| hs-TnT (ng/L) | 8 (5–12) | 15 (7–24)‡ | 15 (9–23)‡ |
| BNP (ng/L) | 47 (24–87) | 89 (36–158)‡ | 91 (36–199)‡ |
| sST2 (ng/mL) | 16.3 (12.8–21.5) | 20.3 (15.2–30.5)‡ | 21.5 (15.4–29.3)‡ |
| Galectin-3 (ng/mL) | 11.0 (9.1–13.4) | 12.0 (9.0–15.6) | 13.0 (10.4–18.6)‡ |
Values are means (SD), number of cases (%) or median (interquartile range).
Abbreviations: BMI = body mass index, BP = blood pressure, AMI = acute myocardial infarction, CCS = Canadian Cardiovascular Society grading of angina pectoris, ACEi = angiotensin converting enzyme, ARB = angiotensin II receptor blocker, CCB = calcium channel blocker, LVEF = left ventricle ejection fraction, LVMI = left ventricle mass index, HbA1c = Glycosylated Hemoglobin, Type A1C, eGFR = estimated glomerulus filtration rate, hs-CRP = high-sensitive C-reactive protein, hs-TnT = highly sensitive Troponin T, BNP = B-type natriuretic peptide, sST2 = soluble ST2.
* p<0.05
† p<0.01 and
‡ p<0.001