Table 1. Baseline characteristics.
| Total (n = 847) | Statin group (n = 202, 23.8%) |
No statin group (n = 645, 76.2%) |
P- value* | |
|---|---|---|---|---|
| Age (years), mean (SD) | 56.69 (6.57) | 57.29 (5.87) | 56.50 (6.77) | 0.139 |
| Men, n (%) | 425 (50.2) | 86 (42.6) | 339 (52.6) | 0.017 |
| Current smoker, n (%) | 153 (18.1) | 39 (19.3) | 114 (17.7) | 0.673 |
| Medication for diabetes mellitus, n (%) | 88 (10.4) | 46 (22.8) | 42 (6.5) | < .001 |
| Medication for hypertension, n (%) | 209 (24.7) | 93 (46.0) | 116 (18.0) | < .001 |
| Metabolic syndrome, n (%) | 545 (64.3) | 186 (92.1) | 359 (55.7) | < .001 |
| Body mass index (kg/m2), mean (SD) | 25.81 (2.95) | 25.92 (3.06) | 25.78 (2.91) | 0.569 |
| Waist circumference (cm), mean (SD) | 89.73 (7.69) | 89.88 (7.68) | 89.69 (7.70) | 0.760 |
| Blood pressure (mmHg), mean (SD) | ||||
| Systolic | 127.60 (14.22) | 125.95 (15.03) | 128.12 (13.93) | 0.057 |
| Diastolic | 84.33 (10.01) | 82.53 (9.55) | 84.89 (10.10) | 0.003 |
| Laboratory findings | ||||
| Total cholesterol (mg/dL), mean (SD) | 191.18 (37.72) | 163.70 (33.98) | 199.78 (34.61) | < .001 |
| HDL-cholesterol (mg/dL), mean (SD) | 49.94 (12.34) | 52.50 (11.77) | 49.13 (12.42) | 0.001 |
| LDL-cholesterol (mg/dL), mean (SD) | 127.15 (37.71) | 98.43 (33.13) | 136.14 (34.44) | < .001 |
| Triglycerides (mg/dL), mean (SD) | 168.98 (125.30) | 147.78 (86.62) | 175.62 (134.53) | 0.006 |
| Fasting glucose (mg/dL), mean (SD) | 101.77 (22.45) | 106.90 (32.40) | 100.16 (17.99) | < .001 |
| hsCRP (mg/dL), mean (SD) | 1.24 (2.51) | 1.00 (1.63) | 1.31 (2.73) | 0.129 |
| CAC | ||||
| CAC, mean (SD) | 46.87 (192.94) | 80.27 (237.91) | 36.42 (175.44) | 0.005 |
| CAC > 0, n (%) | 242 (28.6) | 76 (37.6) | 166 (25.7) | 0.002 |
| Statin intensity, n (%) | ||||
| Low | 10 (5.0) | |||
| Moderate | 180 (89.1) | |||
| High | 12 (5.9) | |||
| Statins, n (%) | ||||
| Atorvastatin | 92 (45.5) | |||
| Fluvastatin | 2 (1.0) | |||
| Pitavastatin | 15 (7.4) | |||
| Pravastatin | 5 (2.5) | |||
| Rosuvastatin | 77 (38.1) | |||
| Simvastatin | 11 (5.4) |
SD, standard deviation; HDL, high-density lipoprotein; LDL, low-density lipoprotein; CAC, coronary artery calcification; hsCRP, high-sensitivity C-reactive protein; p, p-value for the group taking statin and the group not taking statin.
*, χ2 or t-test results.