Fig 4. Dominant functional categories of the genes whose transcript levels are reduced in adenomas of any of the three genera—Mouse, rat, and human.
Functional categories (rows) enriched in the large list of 5477 genes (columns) having decreased transcript levels in tumors in any one of the three genera–mouse, rat, and human from among 19169 annotated genes. 218 populated GO sets showed enrichment at p < 10−5; a subset of these covering the union with low redundancy is shown in the figure. The shaded area in each row counts the number of tumor-associated genes having that functional property; categories are ordered from the top by decreasing numbers of tumor-associated genes not contained in a prior category. Colors indicate the genus in which the transcript level is diminished in adenomas.