Table 2. Effect of the Pde4b genotype on the survival of Apc Min/+ and Apc +/+ mice treated with DSS.
For each cohort of mice, the number surviving to 100 days of age is given in the numerator and the total number in the denominator.
| Genotype | % survival to 100d (n/total) | ||
|---|---|---|---|
| 4% DSS | 2% DSS | No DSS | |
| ApcMin/+ Pde4b+/- | 93.3% (28/30) | 100% (13/13) | 100% (36/36) |
| ApcMin/+ Pde4-/- | 16.7% (3/18) | 100% (5/5) | 100% (18/18) |
| ApcMin/+ Pde4b+/+ | 100% (21/21) | 100% (17/17) | 100% (23/23) |
| Apc+/+ Pde4b+/- | 100% (3/3) | 100% (3/3) | 100% (6/6) |
| Apc+/+ Pde4-/- | 100% (3/3) | 100% (3/3) | 100% (6/6) |
| Apc+/+ Pde4b+/+ | 100% (3/3) | 100% (3/3) | 100% (6/6) |