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. 2018 Sep 6;14(9):e1007658. doi: 10.1371/journal.pgen.1007658

Fig 1. Distribution of ENU-induced mutations in WES data from 107 G1 rescues.

Fig 1

A) Overview of mutation types for the 6,771 observed ENU-induced exonic variants. B) Distribution of missense mutations by nucleotide substitution type. C) Distribution of ENU-variants by chromosome. D) The average number of exonic SNVs is ~65 for both the current (G1-new) and previous (G1-old) screen [5]. E) Number of genes (x-axis) sorted by the number of protein-altering ENU-induced mutations observed per gene (y-axis). Most genes (2,567) carry only 1 mutation. In contrast, the ~0.1 megabase coding region of Ttn carries a total of 15 independent ENU variants.