Table 2. Assumed and literature derived parameters.
Parameter | Symbol | Value | Source |
---|---|---|---|
Incubatory infectiousness, relative to acute illness | rI | 0.5 | Assumption [36,37] |
Subclinical infectiousness, relative to acute clinical illness | rS | 1 | Assumption |
Incubation duration (days)* | PD | Low: Lognormal (2.235, 0.496) | [38] |
High: Lognormal (1.548, 0.344) | |||
Duration of infectiousness (weeks)* | ID | Under 30 years: Lognormal (1.172, 0.483) | [39] |
30 years old +: Lognormal (1.258, 0.788) | |||
Probability of gallstones by age bin (male, female) | pG | 10–19 (0, 0.097) | [15,16] |
20–29 (0.045, 0.234) | |||
30–39 (0.134, 0.431) | |||
40–49 (0.167, 0.517) | |||
50–59 (0.198, 0.60) | |||
60–69 (0.247, 0.692) | |||
70–79 (0.435, 0.692) | |||
80+ (0.40, 0.555) | |||
Long-cycle environmental vehicle decay rate | LD | 0.24/day | [32] |
Dose response† | beta-Poisson(1.75E-01,1.11E+06) | [40] | |
Long-cycle exposure multiplier, 1992–2000 | mEL_D | 0 | Assumption |
Parameters marked with * are lognormal distributions Lognormal(μ,σ), where μ and σ are the fitted mean and standard deviation values of the underlying normal distribution, respectively. Parameter marked with † is a beta-Poisson model parameterized beta-Poisson(α, N50), where α and N50 are derived from published sources [40].