Exhibit 3:

Factors associated with respondents’ opinions about commercialization of biospecimens

	Use	Notification	Preferences for use of profits
	Comfortable with commercial use (question A)	Prefer to be notified about commercial use (question B)	Profits used for research only (question C)	Profits shared with public (charitable trust) (question D)
Recent health experience (past year)
Self or loved one in ER	1.54**	1.32	1.14	1.07
Self or loved one hospitalized	1.24	1.36	1.05	1.18
Support for research
Favorable view of data sharing	2.07****	0.78**	1.50****	1.08
Obligation to participate in research	1.68****	1.05	1.29***	1.24**
Values
Index of privacy concerns	0.74**	2.11****	0.99	1.07
Index of altruism	1.45***	2.28****	2.65****	2.53****
Whether most people can be trusted	1.94****	0.84	1.23**	1.12
Index of trust in the health system	1.28****	0.98	1.16****	1.05
Index of trust in health care providers	2.04****	0.76**	1.60****	1.05

SOURCE Authors’ analysis of data from the 2016 trust in health information sharing survey. NOTES The exhibit shows odds ratios. The full text of each respondent opinion is in exhibit 2. ER is emergency room.

^**p < 0.05

^***p ≤ 0.01

^****p ≤ 0.001