Table 3.

Changes in clinical and behavioral measures from baseline to end of follow up

Variable	Basic		Basic Plus		Treatment Group Difference in Change
Weight (kg)	Mean (SD)	95% CI	Mean (SD)	95% CI	Mean	95% CI
Baselinea	101.63 (20.94)		100.69 (18.70)
Change from baselineb	−1.16	−2.70, 0.37	−1.34	−2.92, 0.24	−0.18	−2.38, 2.03
P for change	0.138		0.097		0.874
Waist (cm)
Baselinea	110.63 (15.56)		112.15 (14.60)
Change from baselinec	−0.68	−2.43, 1.06	−2.48	−4.37, −0.60	−1.79d	−4.36, 0.78
P for change	0.440		0.011		0.169
Systolic BP
Baselinea	119.68 (15.36)		118.63 (15.77)
Change from baselinec	4.46	1.29, 7.62	8.14	4.78, 11.50	3.68e	−0.93, 8.3
P for change	0.006		<.001		0.117
Diastolic BP
Baselinea	73.98 (10.40)		74.54 (10.24)
Change from baselinec	4.37	2.14, 6.60	5.94	3.57, 8.31	1.57e	−1.69, 4.82
P for change	<.001		<.001		0.342

^aBaseline summary statistics for n=261, except for waist circumference where n=195

^bModel-based estimates of treatment effect over time using all measures for all randomized participants and are adjusted for site, gender, and age group.

^cModel-based estimates of treatment effect over time using available measures from 1-year and 2-year or final protocol follow- up visits

^dParticipants with baseline BMI 35–40 (vs. BMI <35) were more likely to have a missing final waist measurement, and those with any prior participation in a weight loss program were less likely to have a missing final waist measurement. Adjusting for these variables resulted in a mean (95% CI) treatment group difference of 2.34 (4.86,0.17), P=0.169.

^eParticipants reporting no change in financial status at baseline were more likely to have a missing final BP measurement. Adjusting for this variable resulted in a mean (95% CI) treatment group difference of 3.71 (−0.91, 8.3), P=0.115, for systolic BP and 1.58 (−1.68, 4.84), P=0.342, for diastolic BP.