Skip to main content
. Author manuscript; available in PMC: 2019 Nov 1.
Published in final edited form as: Mol Neurobiol. 2018 Mar 18;55(11):8438–8454. doi: 10.1007/s12035-018-1004-1

Figure 9. Binding mode of DA at each receptor type.

Figure 9

Shown is the docking orientation of DA at the D3 receptor (A) and α2A (B), and α2C adrenoceptors (C). Residues were scored for binding energy ΔΔG and those most strongly contributing to the binding of DA are shown in stick representation. The strength of binding interaction is colored by the depth of blue with dark blue being the most strongly contributing. Important hydrogen bonds to the amine group and catechol hydroxyls are formed in all binding poses.