Table 2.
Comparison between Poor Responders and Good Responders
| Parameters | Poor responders (n=106) | Good responders (n=64) | p-value |
|---|---|---|---|
| General characteristics | |||
| Sex | 0.757 | ||
| Male | 72 (67.9) | 42 (65.6) | |
| Female | 34 (32.1) | 22 (34.4) | |
| Age, yr | 57.27±9.68 | 60.84±9.14 | 0.018 |
| Child-Pugh score | 6.14±1.11 | 5.92±0.97 | 0.191 |
| Child-Pugh classification | 0.207 | ||
| Class A | 70 (66.0) | 50 (78.1) | |
| Class B | 35 (33.0) | 14 (21.9) | |
| Class C | 1 (1.0) | 0 | |
| Etiology of portal hypertension | 0.854 | ||
| HBV | 56 (52.8) | 37 (57.8) | |
| HCV | 5 (4.7) | 1 (1.6) | |
| Alcohol | 7 (6.6) | 7 (11.0) | |
| PBC | 8 (7.6) | 5 (7.8) | |
| AIH | 7 (6.6) | 2 (3.1) | |
| Schistosomiasis | 4 (3.8) | 2 (3.1) | |
| Cryptogenic | 13 (12.3) | 8 (12.5) | |
| Mixed | 5 (4.7) | 2 (3.1) | |
| Others | 1 (0.9) | 0 | |
| GI bleeding prior to admission | 16 (15.1) | 0 | 0.000 |
| Laboratory Parameters | |||
| Total bilirubin, μmol/L | 20.95±19.30 | 17.73±8.77 | 0.209 |
| Conjugated bilirubin, μmol/L | 9.90±16.83 | 7.75±5.48 | 0.323 |
| Albumin, g/L | 38.30±4.73 | 38.61±4.57 | 0.678 |
| ALT, U/L | 27.21±20.64 | 29.64±14.98 | 0.413 |
| AST, U/L | 34.12±24.30 | 34.73±15.80 | 0.858 |
| Hemoglobin, g/L | 107.33±26.02 | 116.30±22.77 | 0.024 |
| Platelet, ×109/L | 61.27±28.98 | 64.98±29.68 | 0.424 |
| Prothrombin time, s | 13.89±1.31 | 13.49±1.26 | 0.050 |
| Serum creatinine, μmol/L | 73.358±18.40 | 76.70±26.96 | 0.338 |
| No. of endotherapy sessions | 3.54±1.63 | 3.97±1.70 | 0.102 |
| Concurrent conditions | |||
| Portal venous thrombosis | 0.547 | ||
| Absent | 82 (77.4) | 52 (81.3) | |
| Present | 24 (22.6) | 12 (18.7) | |
| Hepatocellular carcinoma | 0.844 | ||
| Absent | 97 (91.5) | 58 (90.6) | |
| Present | 9 (8.5) | 6 (9.4) | |
| Ascites | 0.549 | ||
| Absent | 63 (59.4) | 41 (64.1) | |
| Present | 43 (40.6) | 23 (35.9) | |
| EUS phenomenon | |||
| Para-gastric veins | 0.000 | ||
| Absent | 48 (45.3) | 47 (73.4) | |
| Present | 58 (54.7) | 17 (26.6) | |
| PGV classification | 0.739 | ||
| None | 48 (45.3) | 47 (73.4) | |
| Type 1 | 16 (15.1) | 4 (6.3) | |
| Type 2 | 42 (39.6) | 13 (20.3) | |
| Gastric perforating vein | 0.000 | ||
| Absent | 41 (38.7) | 47 (73.4) | |
| Present | 65 (61.3) | 17 (26.6) | |
| Esophageal perforating vein | 0.000 | ||
| Absent | 37 (34.9) | 40 (62.5) | |
| Present | 69 (65.1) | 24 (37.5) | |
Data are presented as number (%) or mean±SD.
HBV, hepatitis B virus; HCV, hepatitis C virus; PBC, primary biliary cirrhosis; AIH, autoimmune hepatitis; GI, gastrointestinal; ALT, alanine transaminase; AST, aspartate transaminase; EUS, endoscopic ultrasound; PGV, para-gastric vein.