Fig. 7.

Detailed bio-relevant assessment of stability of prodrugs 2 and 25 mimicking various in vivo situations (mean ± SD, n = 3). Bars in orange vertical stripes represent stability of prodrugs when they are spiked in free form. Bars in blue horizontal stripes represent stability of prodrugs when they are spiked in the form of drug-chylomicron (CM) complex. Bars in purple diagonal stripes represent stability tested ex vivo with CM-rich postprandial lymph. **, p < .01. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)