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. 2018 Sep 18;8:13976. doi: 10.1038/s41598-018-32419-w

Table 1.

Metabolic parameters and abdominal fat distribution of the non-diabetic obese, obese type 2 diabetic, and normal weight control groups.

Normal weight Obesity Obesity with diabetes
n 32 32 13
 Age (yr)a 42.8 ± 6.2 32.8 ± 8.8* 45.3 ± 8.1
 BMI (kg/m2)a 22.5 ± 1.6 38.6 ± 5.2* 35.6 ± 6.5*
 Systolic BP (mmHg)a 113 ± 15 137 ± 16* 135 ± 13*
 Diastolic BP (mmHg)b 70 ± 2 83 ± 2* 84 ± 3*
 Glucose (mM)b 5.6 ± 0.2 5.3 ± 0.1 11.9 ± 0.7*,†
 Insulin (pM)b 26.4 ± 3.1 134.9 ± 12.2* 132.4 ± 25.9*
 HOMA-IRb 1.1 ± 0.1 5.3 ± 0.5* 12.3 ± 2.7*,†
 Total cholesterol (mg/dL)a 160 ± 36 182 ± 33 185 ± 52
 HDL-cholesterol (mM)a 12.0 ± 2.6 12.3 ± 2.9 10.0 ± 2.2*,†
 LDL-cholesterol (mM)a 2.6 ± 0.7 3.0 ± 0.8 2.9 ± 1.0
 Triglyceride (mg/dL)b 73 ± 5 146 ± 21* 278 ± 69*,†
 hs-CRP (mg/dL)b 0.08 ± 0.02 0.54 ± 0.09* 0.54 ± 0.12*
 Leptin (ng/mL)b 5.7 ± 0.6 41.7 ± 3.0* 22.2 ± 3.0*,†
 Adiponectin (μg/mL)b 6.7 ± 0.6 2.4 ± 0.3* 3.4 ± 1.4*
 HbA1c (%)b N/A 5.8 ± 0.1 10.0 ± 0.6
Abdominal CT
 TAT area (cm2)a 227 ± 73 654 ± 154* 587 ± 182*
 VAT area (cm2)a 67 ± 30 141 ± 60* 223 ± 50*,†
 SAT area (cm2)a 159 ± 60 513 ± 151* 363 ± 155*,†
 VSRa 0.48 ± 0.25 0.31 ± 0.22* 0.67 ± 0.20*,†

aData are shown as the mean ± SD. bThe data were log-transformed for statistical analysis. Data are shown as the mean ± SE on the original (back-transformed) scale. *p < 0.05 vs. control, p < 0.05 vs. obesity group analyzed using one-way ANOVA followed by Tukey’s post hoc test. N/A, not available.