Table 1.
Normal weight | Obesity | Obesity with diabetes | |
---|---|---|---|
n | 32 | 32 | 13 |
Age (yr)a | 42.8 ± 6.2 | 32.8 ± 8.8* | 45.3 ± 8.1† |
BMI (kg/m2)a | 22.5 ± 1.6 | 38.6 ± 5.2* | 35.6 ± 6.5* |
Systolic BP (mmHg)a | 113 ± 15 | 137 ± 16* | 135 ± 13* |
Diastolic BP (mmHg)b | 70 ± 2 | 83 ± 2* | 84 ± 3* |
Glucose (mM)b | 5.6 ± 0.2 | 5.3 ± 0.1 | 11.9 ± 0.7*,† |
Insulin (pM)b | 26.4 ± 3.1 | 134.9 ± 12.2* | 132.4 ± 25.9* |
HOMA-IRb | 1.1 ± 0.1 | 5.3 ± 0.5* | 12.3 ± 2.7*,† |
Total cholesterol (mg/dL)a | 160 ± 36 | 182 ± 33 | 185 ± 52 |
HDL-cholesterol (mM)a | 12.0 ± 2.6 | 12.3 ± 2.9 | 10.0 ± 2.2*,† |
LDL-cholesterol (mM)a | 2.6 ± 0.7 | 3.0 ± 0.8 | 2.9 ± 1.0 |
Triglyceride (mg/dL)b | 73 ± 5 | 146 ± 21* | 278 ± 69*,† |
hs-CRP (mg/dL)b | 0.08 ± 0.02 | 0.54 ± 0.09* | 0.54 ± 0.12* |
Leptin (ng/mL)b | 5.7 ± 0.6 | 41.7 ± 3.0* | 22.2 ± 3.0*,† |
Adiponectin (μg/mL)b | 6.7 ± 0.6 | 2.4 ± 0.3* | 3.4 ± 1.4* |
HbA1c (%)b | N/A | 5.8 ± 0.1 | 10.0 ± 0.6† |
Abdominal CT | |||
TAT area (cm2)a | 227 ± 73 | 654 ± 154* | 587 ± 182* |
VAT area (cm2)a | 67 ± 30 | 141 ± 60* | 223 ± 50*,† |
SAT area (cm2)a | 159 ± 60 | 513 ± 151* | 363 ± 155*,† |
VSRa | 0.48 ± 0.25 | 0.31 ± 0.22* | 0.67 ± 0.20*,† |
aData are shown as the mean ± SD. bThe data were log-transformed for statistical analysis. Data are shown as the mean ± SE on the original (back-transformed) scale. *p < 0.05 vs. control, †p < 0.05 vs. obesity group analyzed using one-way ANOVA followed by Tukey’s post hoc test. N/A, not available.