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. 2018 Feb 14;25(9):1612–1624. doi: 10.1038/s41418-018-0065-z

Fig. 6.

Fig. 6

Pin1 promotes HCC development by modulating miRNA expression in vivo. a Photograph of SK-Hep1 shCtrl and shPin1 xenografts in nude mice. b Tumor volumes of SK-Hep1 shCtrl and shPin1 xenografts in nude mice. Graphic data shown as the means ± SD. c Pin1 expression in SK-Hep1 shCtrl and shPin1 xenografts was examined by western blotting. d miRNA expression in SK-Hep1 shCtrl and shPin1 xenografts was measured by qPCR. Assays were repeated three times. Error bars represent ± SD. In b and d, statistical significance was determined by the Student’s t-test. **P < 0.01, ***P < 0.001