Fig. 3. The changes in score of each question from after washout with gluten-free for 2 weeks (Fig. 1, V5 or V7) to after gluten challenge with the enzyme mixture or dextrin as placebo for 2 weeks (Fig. 1, V6 or V8).

Questions are related to; Q1, pain or discomfort to the upper abdomen or the pit of the stomach. Q2, nausea. Q3, rumbling in your stomach. Q4, bloating. Q5, diarrhea. Q6, incomplete evacuation feeling. Q7, hunger pains. Q8, low energy level. Q9, headaches. Q10, food craving. Q11, loss of appetite. Q12, health condition related to CD. Q13, Overall health. Q14, physical pain. Q15, comfortable. Q16, healthy. Boxes with hatch marks indicate enzyme administration (GC with E). White boxes indicate placebo (GC with P). Data are expressed as mean ± SE. *p < 0.05