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. 2018 Sep 18;8:14004. doi: 10.1038/s41598-018-32346-w

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Longitudinal myelination imaging following nerve crush injury. (a–d) Myelination indices across the nerve fascicles were calculated (a) immediately before injury and at (b) 7, (c) 14, and (d) 28 days after injury. Quantitative measures of MI along the nerve longitudinal axis are plotted for the common peroneal fascicles. (e–h) The quantitative MI plots corresponding to the projections displayed above in (a–d). The values are obtained from the three-dimensional centerline in the volumetric MI data. The white lines in the projection images represent this centerline. Scale bars = 1 mm.