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. 2018 Sep 18;8:14010. doi: 10.1038/s41598-018-32361-x

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Phylogenetic OTU tree created by LotuS with taxonomic assignment from the eHOMD database. Only OTUs with significantly different relative abundance are depicted with a heat map showing the log2(fold change) within the respective groups used for comparison. The values were highlighted as missing (“NA”), or colored w.r.t. their rounded value. A positive log fold-change indicates a higher relative abundance in the cavitated-caries group, a negative log fold-change stands for higher abundances in the no cavitated-caries group. Match identities according to eHOMD are given following the taxonomic name.