Table 2.

Multivariable models of predictors of intracerebral haemorrhage growth >6 mL

	Comparison	Odds ratio (95% CI)	p value
Patients not taking anticoagulant therapy at symptom onset*
Time from symptom onset to baseline imaging, h†	3·4 vs 1·2	0·65 (0·51–0·82)	0·0003
Intracerebral haemorrhage volume on baseline imaging, mL†	28 vs 7	4·73 (3·81–5·87)	<0·0001
Antiplatelet therapy at symptom onset	Yes vs no	1·38 (1·06–1·79)	0·016
Patients from cohorts including at least some patients taking anticoagulant therapy at symptom onset‡
Time from symptom onset to baseline imaging, h†	3·5 vs 1·2	0·59 (0·42–0·82)	0·0021
Intracerebral haemorrhage volume on baseline imaging, mL†	29 vs 7	4·81 (3·82–6·05)	<0·0001
Antiplatelet therapy at symptom onset	Yes vs no	1·36 (1·04–1·78)	0·023
Anticoagulant therapy at symptom onset	Yes vs no	2·91 (1·97–4·26)	<0·0001

^*Data were calculated on 2534 patients from 18 cohorts (appendix).

^†The odds ratios for time from symptom onset to baseline imaging and intracerebral haemorrhage volume on baseline imaging are for upper quartile compared with lower quartile.

^‡Data were calculated on 2381 patients from ten cohorts (appendix).