Figure 8.

Esculetin inhibits NF-κB signaling in the skin of IMQ-induced psoriasis-like mice. (A) A representative of Western blot images of p-IKKα, IKKα, p-p65, and p65 expressions in the skin of IMQ-induced psoriasis-like mice 7 days after the treatment without or with esculetin. The densitometry analyses of the Western blotting images are shown as the relative expression of p-IKKα/IKKα (B) and p-p65/p65 (C). GAPDH was used as an internal control. Values are expressed as ratios of p-IKKα/IKKα or p-p65/p65. Data are presented as the mean ± SD from four independent experiments (n = 4, *p < 0.05 and **p < 0.01).