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. 2018 Sep 12;9:738. doi: 10.3389/fneur.2018.00738

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Copyright © 2018 Osato, Sato, Osato, Sato, Zhu, Leist, Kuhn and Blomgren.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Proliferation and survival in the subventricular zone (SVZ). (A) Representative microphotographs of the SVZ stained for BrdU in vehicle-treated (Veh) rats without IR (0 Gy), in vehicle-treated rats after IR (6 Gy), and in CEPO-treated rats (CEPO) without or after IR. Bar = 100 μm. (B) There was no difference between the number of BrdU-positive cells in the SVZ of vehicle-treated rats after IR (n = 10) and that without IR (n = 8). The number of BrdU-positive cells in the SVZ of CEPO-treated rats after IR (n = 9) was lower than that of non-irradiated CEPO-treated rats (n = 9) (**p < 0.01). Positive cells were counted as described in the Materials and methods section. Results are presented as mean ± S.E.M.