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. 2018 Sep 12;9:738. doi: 10.3389/fneur.2018.00738

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Copyright © 2018 Osato, Sato, Osato, Sato, Zhu, Leist, Kuhn and Blomgren.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Impact of CEPO on the number of microglia after IR. (A) Representative microphotographs of the SVZ and DG of vehicle- (Veh) and CEPO-treated (CEPO) rat brains without (0 Gy) or after IR (6 Gy) stained for Iba1. Bar = 20 (insert), 100 μm. (B–E) Quantification of microglia in different regions. There was no difference between the numbers of Iba1-positive cells in the SVZ. (B), GCL. (C), hilus. (D), or ML. (E) of vehicle-treated (Veh) rats compared with those of CEPO-treated (CEPO) rats with or without IR (n = 5). Positive cells were counted as described in the Materials and methods section. Results are presented as mean ± S.E.M.