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. 2018 Sep 12;9:2035. doi: 10.3389/fmicb.2018.02035

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Copyright © 2018 Cordeiro, Oliveira, da Silva, Savassi, Acurcio, Lemos, Alves, Assis, Vieira, Faria, Ferreira, Le Loir, Jan, Goulart, Azevedo, Carvalho and do Carmo.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Administration of probiotic beverages improves villus architecture. Morphometric analysis of villus height and crypt depth of animals treated with (A,B) beverages fermented by L. casei BL23; (C,D) beverages fermented by P. freudenreichii 138 or (E,F) beverages fermented by the association of both bacteria following 5-FU or saline administration. Values were obtained by measuring ten random images of the ileum of mice. N = 6, 9. Asterisks represent statistically significant differences as follows: ^∗p < 0.05, ^∗∗p < 0.01, ^∗∗∗p < 0.001, ^∗∗∗∗p < 0.0001.