Table 5.
Linkage disequilibrium and distribution of haplotypes of the two SNPs in TSPAN2 between the cases and controls.
| rs12134493 | rs2078371 | |||||
|---|---|---|---|---|---|---|
| rs12134493 | — | 0.717 (D') | ||||
| rs2078371 | 0.509 (r2) | — | ||||
| Haplotype | Migraine (%) | Control (%) | χ2 | Fisher's p-value | Pearson's p-value | OR (95% CI) |
| A/C | 42.90 (0.050) | 52.62 (0.062) | 1.049 | 0.306 | 0.306 | 0.805 (0.532–1.220) |
| A/T | 25.10 (0.030) | 9.38 (0.011) | 7.319 | 0.007 | 0.007 | 2.728 (1.280–5.811) |
| C/C | 3.10 (0.004) | 30.38 (0.036) | 22.672 | 1.98E-06 | 1.95E-06 | 0.099 (0.031–0.319) |
| C/T | 778.90 (0.916) | 757.62 (0.891) | 3.064 | 0.08 | 0.08 | 1.336 (0.965–1.849) |
CI, confidence interval; OR, odds ratio; n.a., not applicable. Significant p-values are in bold.