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. 2018 Sep 5;9:1019. doi: 10.3389/fphar.2018.01019

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Copyright © 2018 Zhao, Zhu, Cong, Yang and Zhu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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DBT promotes BAT thermogenesis. (A) Ratio of BAT to body weight; (B) Rectal temperature measured at 0900 h; Haematoxylin and eosin staining of BAT (C) and relative mean area (D), scale bar: 20 μm; UCP1 immunohistochemistry of BAT (E) and relative optical density (F); qPCR analysis of the mRNA levels of UCP1 (G) and PGC-1α (H). Results are presented as mean ± SEM (n = 7). ^∗p< 0.05, ^∗∗p< 0.01, ^∗∗∗p< 0.001 compare with HFD group.