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. 2018 Aug 22;16(4):3646–3650. doi: 10.3892/etm.2018.6648

Figure 3.

Figure 3.

Effect of propofol on FOXO1, FOXO3, Bim, pro-caspase-3 and active caspase-3 levels in CRL-7566 cells. After 24 h of treatment with various concentrations of propofol (0, 1, 5 or 10 µg/ml), (A) the protein levels of FOXO1, FOXO3, Bim, pro-caspase-3 and active caspase-3 in CRL-7566 cells were determined by western blot analysis, and (B-D) the mRNA levels of (B) FOXO1, (C) FOXO3 and (D) Bim were determined by reverse-transcription quantitative polymerase chain reaction. Values are expressed as the mean ± standard deviation. *P<0.05, **P<0.01 vs. control group. FOXO, forkhead box O.