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. 2018 Aug 17;16(4):3333–3344. doi: 10.3892/etm.2018.6614

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Copyright: © Guo et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 3. — Effect of Tan IIA on Nrf2 protein expression in DOX-treated mice heart. (A) Representative western blotting and (B) quantitative analysis of total Nrf2 protein expression. (C) Representative western blotting and (D and E) quantitative analysis of nuclear and cytoplasmic Nrf2 protein expression. Data are presented as the mean ± standard error of the mean (n=6). *P<0.05 and ***P<0.001 vs. the control; ^#P<0.05, ^##P<0.01 and ^###P<0.001 vs. DOX. Tan IIA, tanshinone IIA; Nrf2, nuclear factor (erythroid-derived 2)-like 2; DOX, doxorubicin; PCNA, proliferating cell nuclear antigen.