Table 2.
Radiation‐associated sarcoma and treatment characteristics of the 96 patients by radiation‐associated sarcoma
| Characteristic | Total no. of patients | Angiosarcoma, n (%) | Other sarcoma, n (%) |
|---|---|---|---|
| 96 | 50 | 46 | |
| Site | |||
| Breast | 46 (48) | 37 | 9 |
| Upper trunk | 16 (17) | 7 | 9 |
| Ablation scar | 11 (11) | 6 | 5 |
| Shoulder | 6 (6) | 0 | 6 |
| Sternum | 5 (5) | 0 | 5 |
| Axilla | 4 (4) | 0 | 4 |
| Lung | 4 (4) | 0 | 4 |
| Scapula | 3 (3) | 0 | 3 |
| Upper arm | 1 (1) | 0 | 1 |
| Site | |||
| Soft tissue | 88 (92) | 50 | 38 |
| Bone | 8 (8) | 0 | 8 |
| Metastases at presentation | |||
| Yes | 9 (9) | 0 | 9 |
| No | 87 (91) | 50 | 37 |
| Histology | |||
| Angiosarcoma | 50 (52) | ||
| UPS | 27 (28) | ||
| Osteosarcoma | 5 (5) | ||
| Fibrosarcoma | 3 (3) | ||
| Extraskeletal osteosarcoma | 3 (3) | ||
| Chondrosarcoma | 2 (2) | ||
| Leiomyosarcoma | 2 (2) | ||
| Myxofibrosarcoma | 2 (2) | ||
| Extraskeletal chondrosarcoma | 1 (1) | ||
| Neurofibrosarcoma | 1 (1) | ||
| Grade | |||
| 1 | 1 (1) | 0 | 1 (2) |
| 2 | 22 (23) | 8 (16) | 14 (30) |
| 3 | 70 (73) | 39 (78) | 31 (67) |
| Missing | 3 (3) | 3 (6) | 0 |
| Operated with curative intent | |||
| Yes | 82 (85) | 47 (94) | 35 (76) |
| No | 14 (15) | 3 (6) | 11 (24) |
| Adjuvant RTa | |||
| Yes | 9 (11) | 1 (2) | 8 (23) |
| No | 73 (89) | 46 (98) | 27 (77) |
| Adjuvant CTa | |||
| Yes | 9 (11) | 5 (10) | 4 (11) |
| No | 73 (89) | 42 (89) | 31 (89) |
CT, chemotherapy; RAS, radiation‐associated sarcoma; RT, radiation therapy; UPS, undifferentiated pleomorphic sarcoma.
a
Of the 82 patients treated with curative intention.