Table 3.

Factors associated with a false‐positive FIT (ie, no evidence of advanced neoplasia through colonoscopy after a positive FIT), N = 1027

	Unadjusteda			Adjusteda
	OR	95% CI	P	OR	95% CI	P
FIT type
Hemosure vs InSure	1.86	0.50‐6.15	0.32	1.72	0.44‐6.68	0.47
OC‐Micro vs InSure	0.84	0.41‐1.71		0.85	0.37‐1.97
Hemosure vs OC‐Micro	2.23	0.67‐7.46		2.00	0.47‐8.56
Age
50‐64	Ref		0.73
65‐74	1.07	0.74‐1.54
Female	1.71	1.30‐2.26	0.0002	1.59	1.20‐2.11	0.001
Hispanic	1.13	0.72‐1.79	0.59
Non‐white	1.10	0.75‐1.61	0.63
Language
English	Ref		0.17	Ref		0.47
Spanish	1.71	0.97‐3.03		1.44	0.80‐2.60
Other	1.15	0.74‐1.78		1.09	0.69‐1.70
Insurance status
Medicaid	Ref		0.03	Ref		0.09
Medicare	0.84	0.58‐1.22		0.82	0.56‐1.20
Uninsured	1.51	1.07‐2.15		1.40	0.98‐2.01
Commercial	1.10	0.68‐1.78		1.08	0.66‐1.76
Federal poverty level
<100%	Ref		0.87
100%‐150%	0.89	0.60‐1.32
>150%	0.90	0.62‐1.32
Unknown	1.04	0.72‐1.49
Comorbidities
Diabetes	1.18	0.86‐1.60	0.30
Hypertension	1.09	0.82‐1.43	0.56
Colorectal conditionb	2.19	1.16‐4.14	0.02	2.18	1.14‐4.18	0.02
Anticoagulant use	0.98	0.64‐1.50	0.92
NSAIDs use	1.26	0.92‐1.75	0.16	1.17	0.83‐1.62	0.37
Tobacco use
Never	Ref		0.37
Former	0.88	0.62‐1.07
Current	0.76	0.54‐1.07
Unknown	1.08	0.65‐1.79
Season of FIT return
Winter	Ref		0.34
Spring	0.83	0.59‐1.18
Summer	1.10	0.73‐1.68
Fall	1.14	0.76‐1.71

CI, confidence interval; OR, odds ratio.

^aAll models include a random effect for health center, nested within FIT brand, to account for any unmeasured population differences across center. The adjusted model additionally includes FIT kit type and all variables with unadjusted P < 0.20.

^bFrom diagnosis codes present in the EHR within 2 years prior to FIT eligibility (Table S2).