Table 4. Influencing factors associated with good mobilization among the healthy donors.
Good mobilization | The other | P value (univariate) | P value (multivariate) | ||
---|---|---|---|---|---|
Sex | Male | 10 | 13 | 0.29 | |
Female | 3 | 10 | |||
Age at PBSCH | <45 years | 8 | 4 | 0.01 | 0.01 |
>45 years | 5 | 19 | |||
Body weight | <60 kg | 7 | 10 | 0.73 | |
>60 kg | 6 | 13 | |||
Date of PBSCH | Until June 2011 | 3 | 12 | 0.16 | |
Since June 2011 | 10 | 11 | |||
PBSCH modality | Spectra Optia | 4 | 5 | 0.70 | |
COBE Spectra | 9 | 17 | |||
Course of PBSCH | |||||
First course | 13 | 23 | 1 | ||
Second course | 0 | 0 | |||
PBSCH days | Day 1 | 6 | 14 | 0.37 | |
Day 2 | 7 | 7 | |||
Day 3 | 0 | 2 | |||
WBC count | <40,000/µL | 3 | 10 | 0.28 | |
>40,000/µL | 10 | 12 | |||
HPC count | <44/µL | 4 | 16 | 0.01 | 0.03 |
>44/µL | 9 | 5 | |||
Platelet count | <200,000/µL | 8 | 13 | 1 | |
>200,000/µL | 5 | 9 |
Collection of more than 2.0 × 106/kg of CD34+ cells in a single apheresis was defined as good mobilization; PBSCH, peripheral blood stem cell harvest; WBC, white blood cell; HPC, hematopoietic progenitor cell.