Histological and cytological findings in blastic plasmacytoid dendritic neoplasms
(1a-g, case 3). (1a) The oval to spindle
neoplastic cells diffusely proliferate in the dermis. (1b) The
neoplastic cells have scant to modest pale-blue agranular cytoplasm and extend
cytoplasmic pseudopodial projections on bone marrow smears. (1c)
Neoplastic cells in the pleural effusion specimen have ground glass chromatin, a round
nucleus, and some small nucleoli. (1d-g) The neoplastic cells in
formalin-fixed and paraffin-embedded specimens from skin lesions are diffusely
positive for CD123 (1d), CD303 (polyclonal) (1e),
thymic stromal lymphopoietin (1f), and thymic stromal lymphopoietin
receptor (1g).