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. 2018 Feb 8;58(1):1–9. doi: 10.3960/jslrt.17030

Table 1. Clinical features of the patients of BPDCN.

No Age/
Sex
Neoplastic cell
involvement at the
time of diagnosis
G-band Treatment Outcome & neoplastic cell involvement
at the end stage
1 73/
M
Skin, BM (Minimal involvement) Skin sample:
96,XXYY,i(1)(q10),+8,+8,+8,+8,inc(4)
Hyper CVAD/MA Dead, 38 months
Skin, BM, LN, PB, cerebrum, cerebellum
2 83/
M
Skin, BM (Leukemic), LN, PB, spleen BM sample:
45,X,-Y,add(6)(q21),add(9)(q22?),
add(17)(q11.2)[12]/46,XY[4]
Supportive therapy Dead, 5 months
Skin, BM, LN, PB
3 73/
M
Skin, BM (Leukemic), LN, PB BM sample:
46,XY,add(11)(q13),?der(20)t(11;20)(q13;q11.2)[9]/45-46,XY,add(11)(q13),
?der(20)t(11;20)(q13;q11.2)[cp4]/46,XY
Hyper CVAD/MA
Radiation therapy to the
head lesion of skin
Dead, 15 months
Autopsy; Skin, BM, LN, PB, heart, lung, liver, spleen, kidney, pancreas, adrenal gland, thyroid gland, testis, esophagus, urinary bladder, peritoneum
4 37/
M
Skin, BM (Minimal involvement), PB BM sample:
Normal karyotype
Hyper CVAD/MA
Allo-HSCT
Alive, 34 months (on follow-up)
5 35/
M
Skin, BM (Minimal involvement) BM sample:
Normal karyotype
Hyper CVAD/MA
Auto-PBSCT
Alive, 75 months (The follow-up was ended at this time due to the patient’s opinion)
6 74/
M
Skin, BM (Leukemic), PB ND CHOP Alive, 4 months (on follow up)

M, male; BM, bone marrow; LN, lymph node; PB, peripheral blood; CVAD, cyclophosphamide, doxorubicin, vincristine and dexamethasone; MA, methotrexate and cytarabine; Allo-HSCT, allogeneic hematopoietic stem cell transplantation; Auto-PBSCT, autologous peripheral blood stem cell transplantation; CHOP, cyclophosphamide, doxorubicin, vincristine and prednisolone, ND; no data.