Table 4.
Multivariate Cox regression model analysis in patients with ICC
| Overall survival | Recurrence‐free survival | |||||
|---|---|---|---|---|---|---|
| Clinicopathological parameter | HR | 95% CI | P‐value | HR | 95% CI | P‐value |
| α‐SMA expression by CAFs (Positive vs Negative) | 15.896 | 3.711‐68.089 | <0.001 | 20.132 | 4.755‐85.230 | <0.001 |
| Tumor size (≥50 mm vs <50 mm) | 1.657 | 0.984‐2.791 | 0.058 | 2.143 | 1.258‐3.652 | 0.005 |
| Lymph node Metastasis (Present vs Absent) | 2.507 | 1.492‐4.213 | 0.001 | 1.695 | 1.005‐2.859 | 0.048 |
| Tumor number (Multiple vs Single) | — | — | — | 0.764 | 0.421‐1.386 | 0.764 |
| HBV infection (Present vs Absent) | — | — | — | 0.391 | 0.224‐0.681 | 0.001 |