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Change in reported somnolence during intervention period, in 4‐week blocks. Rates of reported somnolence were high, and increased in the first 8 weeks during TIL‐TC150 titration, subsequently dropping during the remaining weeks. There was a reduction in somnolence during the last 4‐week period (weeks 17–20) when compared with the first 8 weeks (r = −0.97).
