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. 2018 Aug 9;5(9):1062–1076. doi: 10.1002/acn3.618

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© 2018 The Authors. Annals of Clinical and Translational Neurology published by Wiley Periodicals, Inc on behalf of American Neurological Association.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Distribution (histogram) of Physiological and Pathological High Frequency Oscillations (physHFO & pathHFO) Frequencies. The distribution of physHFO (blue = task induced outside seizure onset zone (nonSOZ), green = facial pain patients without history of seizures) and pathHFO (red = detected events inside the seizure onset zone (SOZ)) aggregated across patients with excellent outcome (ILAE = 1). The histograms of physHFO and pathHFO show distributions with a peak, characteristic or dominant oscillation frequency, in the high gamma to ripple frequency range.