Table 1.
Comparison of demographics and clinical data between groups defined by in-hospital clinical outcome in 178 patients with sepsis
| Characteristics | Survivors (n=104) |
Non-survivors (n=74) |
P values |
| Age (year) | 78.0 (60.0–84.0) | 78.0 (69.0–84.0) | 0.291 |
| Men | 67 (64.4) | 49 (66.2) | 0.805 |
| Body mass index (kg/m2) | 23.2 (20.4–26.1) | 21.7 (18.4–24.2) | 0.006 |
| Comorbidities | |||
| COPD | 23 (22.1) | 9 (12.2) | 0.088 |
| Diabetes mellitus | 26 (25.0) | 21 (28.4) | 0.614 |
| Hypertension | 47 (45.2) | 31 (41.9) | 0.662 |
| Cerebrovascular disease | 30 (28.8) | 15 (20.3) | 0.194 |
| Neoplasm | 18 (17.3) | 12 (16.2) | 0.848 |
| Liver disease | 5 (4.8) | 4 (5.4) | 1.000 |
| Heart failure | 20 (19.2) | 14 (18.9) | 0.958 |
| Chronic renal failure | 18 (17.3) | 11 (14.9) | 0.664 |
| Smoking (pack years) | 0 (0–30.0) | 0 (0–16.3) | 0.509 |
| Primary site of infection | |||
| Lung | 77 (74.0) | 54 (73.0) | 0.874 |
| Abdomen | 10 (9.6) | 5 (6.8) | 0.499 |
| Urinary tract | 7 (6.7) | 6 (8.1) | 0.728 |
| Gastrointestinal tract | 7 (6.7) | 5 (6.8) | 1.000 |
| Other site | 3 (2.9) | 4 (5.4) | 0.452 |
| Community-acquired infection | 85 (81.7) | 50 (67.6) | 0.030 |
| Hypotension | 22 (21.2) | 41 (55.4) | <0.001 |
| Lactate level (mmol/L) | 1.8 (1.0–3.4) | 2.7 (1.5–5.7) | 0.001 |
| Oliguria | 8 (7.7) | 16 (21.6) | 0.007 |
| Pao2/Fio2 (mm Hg) | 198.5 (119.3–287.5) | 152.5 (99.6–210.3) | 0.006 |
| Serum creatinine (µmol/L) | 97.0 (68.3–176.3) | 108.5 (64.0–194.3) | 0.868 |
| Total bilirubin (µmol/mL) | 13.1 (9.9–22.3) | 18.0 (12.5–32.8) | 0.015 |
| Platelets (×109/L) | 161.0 (95.8–232.5) | 123.0 (75.0–204.3) | 0.067 |
| INR | 1.2 (1.0–1.4) | 1.3 (1.1–1.6) | 0.015 |
| Glasgow Coma Scale | 15.0 (10.0–15.0) | 13.0 (10.0–15.0) | 0.117 |
| SOFA score | 5.0 (4.0–7.0) | 9.0 (7.0–11.0) | <0.001 |
| APACHE II score | 16.0 (12.0–22.0) | 21.0 (17.0–30.0) | <0.001 |
| Septic shock | 21 (20.2) | 38 (51.4) | <0.001 |
| Non-invasive ventilation | 28 (26.9) | 24 (32.4) | 0.426 |
| Intubated | 36 (34.6) | 43 (58.1) | 0.002 |
| Positive blood culture | 19 (18.3) | 19 (25.7) | 0.235 |
| Length of ICU stay (days) | 12.0 (6.0–22.0) | 12.0 (3.0–25.0) | 0.521 |
| Length of hospital stay (days) | 18.0 (10.0–30.0) | 13.0 (3.0–25.0) | 0.009 |
Data are presented as n (%) or median (IQR) unless stated otherwise.
APACHE, Acute Physiology and Chronic Health evaluation; COPD, chronic obstructive pulmonary disease; ICU, intensive care unit; INR, international normalised ratio; SOFA, Sequential Organ Failure Assessment.