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Liriodenine significantly decreases DSB repair in ECA-109 cells. (A) γ-H2AX foci was evaluated by immunofluorescence. (B) Irradiated ECA-109 cells were treated with or without liriodenine for 2, 12 and 24 h. The mean numbers of γ-H2AX foci were calculated to show the degree of DSBs. Cells were co-stained with DAPI to visualize nuclei. Magnification ×40. *P<0.05 vs. 8 Gy at 2 h. DSB, double strand break; γ-H2AX, γ-histone 2AX.
