Table I.
The baseline characteristics of the SCM cases extracted from the SEER database.
| DSS | OS | |||||
|---|---|---|---|---|---|---|
| Parameters | Alive | Dead | P-value | Alive | Dead | P-value |
| Age | ||||||
| ≤66 years | 1,333 | 361 | <0.001 | 1,512 | 621 | <0.001 |
| >66 years | 710 | 406 | 1,095 | 1,533 | ||
| Sex | ||||||
| Female | 878 | 274 | <0.001 | 1,066 | 763 | <0.001 |
| Male | 1,165 | 493 | 1,541 | 1,391 | ||
| Ethnicity | ||||||
| White | 1,947 | 745 | 0.009 | 2,506 | 2,098 | 0.008 |
| Black | 16 | 9 | 17 | 17 | ||
| Others | 80 | 13 | 84 | 39 | ||
| Tumor location | ||||||
| Eyes and bony orbits | 383 | 118 | <0.001 | 433 | 294 | <0.001 |
| Internal organs | 7 | 14 | 9 | 21 | ||
| Nose and mouth | 18 | 20 | 19 | 29 | ||
| Skin | 1,624 | 587 | 2,131 | 1,766 | ||
| Other site | 11 | 28 | 15 | 44 | ||
| Grade | ||||||
| I | 26 | 4 | <0.001 | 30 | 8 | <0.001 |
| II | 16 | 1 | 20 | 8 | ||
| III | 16 | 20 | 20 | 40 | ||
| IV | 12 | 16 | 15 | 31 | ||
| Unknown | 1,973 | 726 | 2,522 | 2,067 | ||
| AJCC stage | ||||||
| I | 552 | 42 | <0.001 | 745 | 184 | <0.001 |
| II | 533 | 118 | 729 | 371 | ||
| III | 138 | 57 | 176 | 115 | ||
| IV | 36 | 73 | 50 | 115 | ||
| T stage | ||||||
| T0 | 22 | 26 | <0.001 | 30 | 40 | <0.001 |
| T1 | 394 | 38 | 524 | 148 | ||
| T2 | 345 | 44 | 451 | 154 | ||
| T3 | 244 | 60 | 347 | 178 | ||
| T4 | 278 | 117 | 375 | 284 | ||
| TX | 99 | 42 | 144 | 125 | ||
| N stage | ||||||
| N0 | 1,226 | 210 | <0.001 | 1,656 | 683 | <0.001 |
| N1 | 57 | 46 | 77 | 79 | ||
| N2 | 35 | 16 | 46 | 38 | ||
| NX | 65 | 55 | 93 | 129 | ||
| M stage | ||||||
| M0 | 1,324 | 246 | <0.001 | 1,796 | 779 | <0.001 |
| M1 | 34 | 73 | 48 | 114 | ||
| MX | 25 | 8 | 28 | 36 | ||
| SEER stage | ||||||
| Localized | 1,499 | 305 | <0.001 | 1,893 | 1,133 | <0.001 |
| Regional | 419 | 263 | 547 | 632 | ||
| Distant | 8 | 9 | 14 | 18 | ||
| Unknown | 70 | 53 | 88 | 143 | ||
| Treatment | ||||||
| Non-surgery | 208 | 109 | 0.011 | 266 | 255 | 0.195 |
| Surgery | 1,827 | 655 | 2,332 | 1,891 | ||
| Unknown | 8 | 3 | 9 | 8 | ||
SCM, spindle cell melanoma; OS, overall survival; DSS, disease specific survival; T, tumor; N, node; M, metastasis; SEER, the Surveillance, Epidemiology and End Results; AJCC stage, American joint committee on cancer stage. TX, T stage unknown; NX, N stage unknown; MX, M stage unknown.