Figure 3.

circRNA expression in hematopoietic cells. (A) Number of high confidence circRNA detection, as defined by ≥ 2 junction reads in each replicate of one specific cell population). 33 out of the 489 circRNA were newly identified. (B, C) PCA plot (B) and (C) unsupervised Pearson correlation clustering (row-scaled RPM) of the circRNA expression in the hematopoietic populations depicted in a heat map (n = 2–3 per cell type). (D, E) Sum of different circRNA expressed per cell type (D), and of the overall number of circRNA expressed per population (E). n = 2–3, error bar depicts standard deviation. RPM: reads per million mapped reads.