miR-27a promotes the cell cycle of PCa cells. (A) Flow cytometry reveals the cell cycle of PCa cells, including G1, S and G2 stages. (B) The PCa cells transfected with miR-27a mimics exhibited a higher number of S-stage cells compared with those transfected with the NC, and the overexpression of SPRY2 rescued miR-27a-induced high S stage. **P<0.01 vs. NC. miR, microRNA; SPRY2, Sprouty2; PCa, prostate cancer; NC, negative control.