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. 2018 Aug 14;16(4):5160–5166. doi: 10.3892/ol.2018.9305

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Copyright: © Wan et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 1. — Identification of the most effective siRNA for lncRNA PVT1-knockdown. (A) si-RNA-2# was the most effective for knockdown of lncRNA PVT1 expression. (B) lncRNA PVT1 expression was significantly knocked down in PC3 cells. (C) lncRNA PVT1 expression was significantly knocked down in DU145 cells. (D) Efficiency of lentivirus-mediated RNAi was tested in PC3 cells (magnification, ×100). (E) Efficiency of lentivirus-mediated RNAi was tested in DU145 cells (magnification, ×100). *P<0.05 vs. NC group, **P<0.01 vs. NC group. siRNA, small interfering RNA; lncRNA, long non-coding RNA; NC, negative control; RNAi, RNA interference; GFP, green fluorescent protein.