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. 2018 Aug 14;16(4):5131–5139. doi: 10.3892/ol.2018.9307

Figure 4.

Figure 4.

PDCD4, p-Akt and p-ERK protein expression levels are decreased in HCT116 cells treated with miR1260b inhibitor and/or 5-FU. (A) Protein expression levels of PDCD4, p-AKT and p-ERK following treatment with 5-FU and/or miR-1260b inhibitor, as detected by western blotting. (B) Quantification of the protein expression levels of PDCD4 (*P<0.05, **P<0.01 vs. control group; ##P<0.01 vs. 5-Fu alone treatment group). (C) Quantification of the protein expression levels of p-Akt (*P<0.05, **P<0.01 vs. control group, #P<0.01 vs. 5-FU alone treatment group). (D) Quantification of the protein expression levels of p-ERK (**P<0.01 vs. control group, ##P<0.01 vs. 5-FU alone treatment group). PDCD4, programmed cell death receptor 4; p-phosphorylated; ERK, extracellular-signal-regulated kinase; 5-FU, 5-fluorouracil; miR, microRNA.