Table 2.
Characteristics | Subgroups | Event | Total | Menstruation return mean ± s.d. (months) | P Value |
---|---|---|---|---|---|
Age | <40 | 16 | 22 | 13.2 ± 3.2 | |
≥40 | 36 | 60 | 23.4 ± 2.9 | 0.009 | |
BMI | <27 | 44 | 69 | 22.0 ± 2.6 | |
≥27 | 8 | 13 | 12.6 ± 3.7 | 0.104 | |
Chemotherapy regimen | Anthracycline + cyclophosphamide | 30 | 42 | 16.6 ± 2.9 | – |
Anthracycline + cyclophosphamide followed by taxane | 14 | 27 | 21.7 ± 3.8 | 0.092 | |
Anthracycline + taxane | 8 | 13 | 31.1 ± 6.7 | 0.205 | |
Oestradiol | Ovarian failure (<37 pg/mL) | 46 | 74 | 22.1 ± 2.5 | |
Functional ovarian reserve (≥37 pg/mL) | 6 | 8 | 6.9 ± 1.7 | 0.003 | |
Anti-Müllerian hormone | Ovarian failure (<800 pg/mL) | 4 | 9 | 34.1 ± 7.7 | |
Functional ovarian reserve (≥800 pg/mL) | 48 | 73 | 18.5 ± 2.3 | 0.026 | |
Inhibin B | Ovarian failure (<30 pg/mL) | 19 | 32 | 14.4 ± 2.4 | |
Functional ovarian reserve (≥30 pg/mL) | 33 | 50 | 23.4 ± 3.1 | 0.263 |