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. 2018 Jul 19;16(4):4159–4168. doi: 10.3892/ol.2018.9175

Table I.

Basic characteristics of the breast cancer datasets.

Dataset Sample type Assay type miRNA probes, n Method of validation
SY (23) Three human breast tumors Multiplex Real-time PCR Assay (Applied Biosystems; Thermo Fisher Scientific, Inc.) b- Breast cancer cell colony formation assay
IM (11) 10 normal and 76 neoplastic breast tissues miRNA microarray chip (KCI version 1.0) and Perkin-Elmer ScanArray XL5K 368 Northern blotting
HH (25) 148 patients with BC and 44 age-matched and disease-free controls TaqMan (Applied Biosystems; Thermo Fisher Scientific, Inc.) RT-qPCR
LA (26)
KL (27) MCF-7 and MDA-MB-231 cell lines RT2 miRNA PCR array system (SABiosciences™ Corporation, Frederick, MD, USA) 376 RT-qPCR
YL (28) 113 BC and 40 paired non-cancerous NATs CapitalBio (http://www.capitalbio.com) 509 RT-qPCR
SH (29) 48 tissue and 100 serum samples of patients with primary BC and 20 control samples 10 RT-qPCR
VS (40) 63 primary tumors and 177 normal tissues Bead-based microRNA profiling platform 40-mer Northern blotting

BC, breast cancer; RT-qPCR, reverse transcription quantitative polymerase chain reaction; miRNA, microRNA; NATs, normal adjacent tumor tissues; -, data not available from the orignal datasets.