Figure 5.

Replication of EHV1 in equine respiratory mucosa explants and equine respiratory epithelial cell (EREC) cultures following treatment with rEqIFNα. The efficacy of rEqIFNα treatment was measured by the extracellular virus titer of IFN-treated explants and cells. Each symbol represents one horse. Experiments were performed on 3 individual horses. Different horses were used to isolate mucosa explants (horse 1●, 2 ■, and 3 ▲) and EREC (horse I ○, II □, and III △). Different small letters represent significant differences (p < 0.05) in virus titers.