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. 2018 Sep 1;31(7):486–491. doi: 10.1089/vim.2018.0032

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© Sayuri Hara et al., 2018; Published by Mary Ann Liebert, Inc.

This Open Access article is distributed under the terms of the Creative Commons Attribution Noncommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and the source are cited.

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FIG. 4. — Estradiol increased the ratio of IgG to IgG and IgM (IgG/IgG + IgM) in patients. Pileup production of Ig in healthy controls (a) and patients (b). The ratio of IgG to IgG and IgM (IgG/IgG + IgM) in healthy controls (c) and patients (d). In patients, the IgG/IgG + IgM ratio increased between 0 and 1 nM estradiol (p = 0.063) and between 0 and 100 nM estradiol (p = 0.128).