Table 1.
Total Calcium Quintiles |
Total Dairy Products Quintiles |
|||||||
---|---|---|---|---|---|---|---|---|
1 (n = 4,284) |
3 (n = 4,285) |
5 (n = 4,285) |
Pb | 1 (n = 3,439) |
3 (n = 4,256) |
5 (n = 4,438) |
Pb | |
Demographics | ||||||||
Age, years | 63.8 ± 9.1 | 64.6 ± 9.6 | 66.6 ± 9.2 | <0.0001 | 64.4 ± 8.8 | 64.6 ± 9.2 | 65.4 ± 9.7 | <0.0001 |
Male, % | 44.1 | 44.1 | 44.1 | 1.00 | 58.4 | 42.0 | 41.8 | <0.0001 |
White, % | 49.6 | 66.5 | 81.6 | <0.0001 | 47.5 | 68.5 | 80.8 | <0.0001 |
Region, Stroke Belt,c % | 31.1 | 31.2 | 32.8 | <0.0001 | 33.7 | 34.3 | 33.7 | <0.0001 |
Medical history,d % | ||||||||
Heart disease | 17.3 | 17.2 | 16.5 | 0.05 | 18.8 | 16.1 | 17.6 | 0.0002 |
Diabetes | 23.7 | 20.3 | 15.3 | <0.0001 | 20.8 | 19.1 | 19.8 | 0.39 |
Cancer | 7.6 | 8.6 | 11.6 | <0.0001 | 9.1 | 8.0 | 10.6 | <0.0001 |
College graduate or higher, % | 28.5 | 38.5 | 44.9 | <0.0001 | 32.2 | 38.1 | 40.9 | <0.0001 |
Annual income $35,000+, % | 43.0 | 49.0 | 50.8 | <0.0001 | 43.1 | 50.5 | 48.6 | <0.0001 |
Lifestyle Factors | ||||||||
Current smokers, % | 41.7 | 46.1 | 49.2 | <0.0001 | 39.1 | 44.9 | 48.7 | <0.0001 |
Moderate alcohol consumption (0–14 M, 0–7 F drinks/week), % | 30.3 | 36.0 | 38.4 | <0.0001 | 33.4 | 35.9 | 36.0 | <0.0001 |
Body mass index, kg/m2 | 30.0 ± 6.5 | 29.3 ± 6.4 | 28.1 ± 5.9 | <0.0001 | 29.2 ± 5.9 | 29.3 ± 6.3 | 28.8 ± 6.3 | <0.0001 |
Physical activity, ≥ 1 times/week, % | 25.8 | 29.1 | 35.8 | <0.0001 | 27.2 | 29.4 | 33.0 | <0.0001 |
NSAID or aspirin use, % | 47.2 | 51.1 | 57.8 | <0.0001 | 49.1 | 53.8 | 53.9 | <0.0001 |
HRT, % females | 49.8 | 57.7 | 67.0 | <0.0001 | 22.7 | 34.8 | 35.7 | <0.0001 |
Dietary Intakes | ||||||||
Total energy, kcal/day | 1,211 ± 401 | 1,853 ± 682 | 2,043 ± 779 | <0.0001 | 1,440 ± 629 | 1,692 ± 679 | 2,049 ± 753 | <0.0001 |
Total fat, % total energy | 37.4 ± 8.5 | 37.6 ± 7.7 | 36.3 ± 7.5 | <0.0001 | 37.2 ± 8.7 | 38.0 ± 7.6 | 35.9 ± 7.6 | <0.0001 |
Saturated fat, g/day | 14.2 ± 6.1 | 22.8 ± 10.7 | 24.2 ± 12.1 | <0.0001 | 15.9 ± 8.5 | 20.6 ± 10.0 | 25.4 ± 12.3 | <0.0001 |
Dietary fiber, g/day | 10.3 ± 4.7 | 17.0 ± 7.7 | 20.8 ± 0.1 | <0.0001 | 13.4 ± 7.9 | 15.9 ± 8.0 | 19.0 ± 9.4 | <0.0001 |
Total calcium, mg/day | 343 ± 90 | 887 ± 163 | 1,896 ± 351 | <0.0001 | 602 ± 436 | 928 ± 480 | 1,534 ± 570 | <0.0001 |
Dietary calcium | 316 ± 90 | 719 ± 210 | 999 ± 425 | <0.0001 | 351 ± 174 | 581 ± 180 | 1,133 ± 333 | <0.0001 |
Supplemental calcium | 27.4 ± 52.5 | 168 ± 245 | 897 ± 386 | <0.0001 | 252 ± 398 | 347 ± 448 | 401 ± 472 | <0.0001 |
Total vitamin D, IU/day | 153 ± 155 | 332 ± 203 | 495 ± 224 | <0.0001 | 219 ± 194 | 297 ± 195 | 482 ± 245 | <0.0001 |
Total meat, servings/day | 1.5 ± 0.8 | 2.1 ± 1.3 | 2.2 ± 1.3 | <0.0001 | 1.8 ± 1.2 | 2.0 ± 1.2 | 2.1 ± 1.3 | <0.0001 |
Total fruit and vegetable, servings/day | 1.9 ± 1.3 | 3.2 ± 2.1 | 3.8 ± 2.7 | <0.0001 | 2.4± 2.1 | 3.0 ± 2.1 | 3.4 ± 2.4 | <0.0001 |
Total dairy, servings/d | 2.3 ± 1.8 | 8.1 ± 4.8 | 13.0 ± 8.6 | <0.0001 | 0.9 ± 0.7 | 5.5 ± 0.9 | 17.8 ± 5.9 | <0.0001 |
Whole milk, servings/week | 0.3 ± 0.8 | 0.7 ± 2.4 | 0.9 ± 3.9 | <0.0001 | 0.1 ± 0.2 | 0.5 ± 1.3 | 1.6 ± 4.9 | <0.0001 |
Reduced/low-fat milk, servings/week | 1.2 ± 2.3 | 4.6 ± 7.5 | 6.0 ± 11.7 | <0.0001 | 0.3 ± 0.6 | 3.0 ± 3.8 | 8.9 ± 13.8 | <0.0001 |
Skim milk, servings/week | 0.1 ± 0.6 | 1.2 ± 3.3 | 3.2 ± 6.4 | <0.0001 | 0.03 ± 0.2 | 0.6 ± 1.4 | 4.3 ± 7.2 | <0.0001 |
Abbreviations: HRT, hormone replacement therapy; NSAID, non-steroidal anti-inflammatory drug.
Continuous variables are presented as means ± standard deviations; categorical variables are presented as percentages.
P values from Chi-square test for categorical variables and analysis of variance for continuous variables.
Stroke Belt defined as Alabama, Arkansas, Georgia, Louisiana, Mississippi, North Carolina, South Carolina, and Tennessee; otherwise, live in other continental US states.
Medical history of heart disease including self-reported myocardial infarction, coronary bypass grafting, cardiac bypass, angioplasty, stenting, or evidence of myocardial infarction via electrocardiogram; self-reported diabetes; history of any type of cancer.